Located in Key Largo, Holiday Inn Key Largo by IHG is in the business district, a 1-minute drive from Jimmy Johnson's Big Chill and 7 minutes from MarineLab Undersea Laboratory. This beach hotel is 3.4 mi (5.5 km) from John Pennekamp Coral Reef State Park and 4.4 mi (7 km) from Caribbean Club Bar.

Make yourself at home in one of the 132 air-conditioned rooms featuring refrigerators and LCD televisions. Complimentary wired and wireless internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers. Conveniences include safes and coffee/tea makers, as well as phones with free local calls.

Dip into one of the 2 outdoor swimming pools or enjoy other recreational amenities, which include a 24-hour fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and gift shops/newsstands.

Grab a bite at one of the hotel's 2 restaurants, or stay in and take advantage of the room service (during limited hours). Relax with a refreshing drink from the poolside bar or one of the 2 bars/lounges. Buffet breakfasts are available daily from 7:00 AM to 11:00 AM for a fee.

Featured amenities include complimentary wired internet access, a 24-hour business center, and a 24-hour front desk. Event facilities at this hotel consist of conference space and 3 meeting rooms. Free self parking is available onsite.